Cancer cure latest news update: Will a modified CAR-T cell treatment completely eradicate brain tumors?
A recent cancer cure found in the form of CAR-T cell treatment could be the medical breakthrough that will change the tide in modern medicine's battle against cancer.
As reported by iTech Post, a new form of cancer treatment could extinguish some forms of hard-to-cure malignancies — including breast cancer and lung cancer — which could often lead to death.
Scientists at the City of Hope cancer center located in Duarte, California reportedly administered, for the first time in medical history, CAR-T cell treatment through the brain of patient with brain tumors. This differs from the usual administration of the therapy through the blood.
The experimental treatment was done by infusing genetically modified T-cells, which were specially designed to attack and kill cancerous cells, into a small area of the human brain where spinal fluid is produced.
"The idea was to have the flow of the spinal fluid carry the T cells to different locations," Dr. Behnam Badie, neurosurgery chief at City of Hope, reportedly told the Associated Press, according to the International Business Times.
The objective of the experiment was to see if the T-cells spread by the spinal fluid throughout the body would be able to reduce the size of tumors located in the brain and in different areas of the body, in contrast to targeting specific areas of the body.
One of the City of Hope's patients was given six infusions of the T-cells every week through a small tube connected to his brain after having undergone surgical removal of three of his largest tumors. Results showed not only reduction in the size of the remaining tumors in the brain, but researchers allegedly saw all the tumors disappear after the administration of the tenth treatment.
Eventually, the researchers did note that the tumors have reappeared in other regions of the brain, although cancer never recurred in the areas where the original tumors were eradicated from.
Two other patients at City of Hope underwent the same trial. However, the experiment was not able to yield similar results. Side effects were also noted to have potentially been brought about by the experimental treatment.
The results of the experiment, although still at its infancy, is believed to be a fundamental breakthrough which opens up a new path for cancer research. Hence, the California-based hospital will reportedly continue in studying and modifying the experimental treatment in the hopes that it could be a better method of treating cancer.